Publications

  1. Cho SE, Li W, Beard AM, Jackson JA, Kiernan R, Hoshino K, Martin AC, Sun J. Actomyosin contraction in the follicular epithelium provides the major mechanical force for follicle rupture during Drosophila ovulation. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2407083121. doi: 10.1073/pnas.2407083121. Epub 2024 Sep 18. PMID: 39292751; PMCID: PMC11441566. https://pubmed.ncbi.nlm.nih.gov/39292751/
  2. Zeng, B., Knapp, E. M., Skaritanov, E., Oramas, R. and Sun, J. (2024). ETS transcription factors regulate precise matrix metalloproteinase expression and follicle rupture in Drosophila. Development 151, dev202276. https://pubmed.ncbi.nlm.nih.gov/38345299/
  3. Berg, C., Sieber, M. and Sun, J. (2023). Finishing the egg. Genetics iyad183. https://doi.org/10.1093/genetics/iyad183
  4. Oramas, R., Knapp, E. M., Zeng, B. and Sun, J. (2023). The bHLH-PAS transcriptional complex Sim:Tgo plays active roles in late oogenesis to promote follicle maturation and ovulation. Development 150, dev201566. https://pubmed.ncbi.nlm.nih.gov/37218521/
  5. Jiang, K., Zhang, J., Huang, Y., Wang, Y., Xiao, S., Hadden, M.K., Woodruff, T.K., and Sun, J. (2021). A platform utilizing Drosophila ovulation for nonhormonal contraceptive screening. PNAS 118 (28) e2026403118; https://doi.org/10.1073/pnas.2026403118
  6. Knapp EM, Li W, Singh V, Sun J. (2020). Nuclear receptor Ftz-f1 promotes follicle maturation and ovulation partly via bHLH/PAS transcription factor Sim. eLife  doi: 10.7554/eLife.54568
  7. Shen, W. and Sun, J. (2020). Different modes of Notch activation and strength regulation in the spermathecal secretory lineage. Development dev.184390.
  8. Knapp, E.M., Li, W., and Sun, J. (2019). Downregulation of homeodomain protein Cut is essential for follicle maturation and ovulation. Development dev.179002.
  9. Knapp, E.M., Deady, L.D. and Sun, J. (2018). Ex vivo Follicle Rupture and in situ Zymography in Drosophila. BIO-PROTOCOL 8, e2846.
  10. Li, W., Young, J.F., and Sun, J. (2018). NADPH oxidase-generated reactive oxygen species in mature follicles are essential for Drosophila ovulation. PNAS 115, 7765–7770. https://doi.org/10.1073/pnas.1800115115
  11. Deady, L.D., Li, W., and Sun, J. (2017). The zinc-finger transcription factor Hindsight regulates ovulation competency of Drosophila follicles. eLife. e29887.
  12. Shen, W., and Sun, J. (2017). Dynamic Notch Signaling Specifies Each Cell Fate in Drosophila Spermathecal Lineage. G3: Genes, Genomes, Genetics g3.117.040212.
  13. Knapp, E.M., and Sun, J. (2017). Steroid signaling in mature follicles is important for Drosophila ovulation. PNAS 201614383. doi: 10.1073/pnas.1614383114.
  14. Deady, L.D., Sun, J. (2015). A Follicle Rupture Assay Reveals an Essential Role for Follicular Adrenergic Signaling in Drosophila Ovulation. PLoS Genetics 11(10): e1005604. doi:10.1371/journal.pgen.1005604
  15. Deady, L.D., Shen W., Mosure S.A., Spradling, A.C., Sun, J. (2015). Matrix Metalloproteinase 2 Is Required for Ovulation and Corpus Luteum Formation in Drosophila. PLoS Genetics 11: e1004989 doi:10.1371/journal.pgen.1004989

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  1. Sun, J., and Spradling, A.C. (2013). Ovulation in Drosophila is controlled by Secretory Cells of the Female Reproductive Tract. eLife. DOI: http://elifesciences.org/content/2/e00415v1
  2. Sun, J., and Spradling, A.C. (2012). NR5A Nuclear Receptor Hr39 Controls Three-Cell Secretory Unit Formation in Drosophila Female Reproductive Glands. Current Biology 22, 862–871
  3. Poulton, J.S., Huang, Y.-C., Smith, L., Sun, J., Leake, N., Schleede, J., Stevens, L.M., and Deng, W.-M. (2011). The MicroRNA Pathway Regulates the Temporal Pattern of Notch Signaling in Drosophila Follicle Cells. Development 138, 1737–1745
  4. Shyu, L.-F.*, Sun, J.*, Chung, H.-M., Huang, Y.-C., and Deng, W.-M. (2009). Notch Signaling and Developmental Cell-Cycle Arrest in Drosophila Polar Follicle Cells. Molecular Biology of the Cell 20, 5064–5073 *Co-first authors
  5. Sun, J., Smith, L., Armento, A., and Deng, W.-M. (2008). Regulation of the Endocycle/Gene Amplification Switch by Notch and Ecdysone signaling. Journal of Cell Biology. 182, 885–896
  6. Sun, J., and Deng, W.-M. (2007). Hindsight Mediates the Role of Notch in Suppressing Hedgehog Signaling and Cell Proliferation. Developmental Cell 12, 431–442
  7. Sun, J., and Deng, W.M. (2005). Notch-dependent Downregulation of the Homeodomain Gene Cut is Required for the Mitotic Cycle/Endocycle Switch and Cell Differentiation in Drosophila Follicle Cells. Development 132, 4299–4308
  8. Shi, Q., Wang, Q., Chen, Y., Sun, J, Ge, Y., Zhang, X.. 2006. Construction of Human Breast Carcinoma Cell Line Transfected with OX40L and Its Costimulatory Effect on T Cells. AiZheng. 25:148-52
  9. Shi, Q., Chen, Y., Sun, J., Mang, H., Jiang, Z., Mao, Y., Zhang, X. (2005). Expression of Human OX40L in BL21 E. coli and Studies on Its Biological Function. Chinese Journal of Immunology. 21, 163-171
  10. Wang, Q., Chen, Y., Ge, Y., Sun, J., Shi, Q, Ju, S., Dai, J., Yu, G., Zhang, X.. 2004. Characterization and Functional Study of Five Novel Monoclonal Antibodies Against Human OX40L Highlight Reverse Signaling: Enhancement of IgG Production of B Cells and Promotion of Maturation of DCs. Tissue Antigens. 64:566-74
  11. Wang, Q., Chen, Y., Sun., J., Shi, Q., Ju, S., Yu, G., Chen, J., Zhang, X. 2004. Preparation of Anti-human OX40L Functional Monoclonal Antibody and Characterization of Its Biological Activities. Chinese Journal of Microbiology and Immunology. 24, 790-793
  12. Wang, Q., Sun, J., Shi, Q., Chen, Y., Dai, J., Chen, J., Su, Y., Zhang, X. 2004. Construction of the Transfected Cell Line Expressing the Human OX40L Gene and Its Costimulation to T cells. Current Immunology. 24, 99-103
  13. Ge, Y., Chen, Y., Shi, Q., Sun, J., Wang, Q., Zhang, X. 2004. Comparison of Two Eukaryonic Expression Systems. Chinese Journal of Immunology. 20, 46-49
  14. Sun, J., Shi, Q., Wang, Q., Zhang, X. 2003. Construction of Human OX40-transfected Cell Line and Its Function to Induce Differentiation of Dendritic Cells. Shanghai Journal of Immunology. 23: 370-373
  15. Chen, Y., Shi, Q., Ge, Y., Xu, K., Gu, T., Sun, J., Li, W., Zhang, X. 2003. Gene Cloning of Human PD-L1( B7-H1) and the Corresponding Recombinant Retrovirus Construction and Stable Expression. Chinese Journal of Cancer Biotherapy. 10, 110-114